Plavix clopidogrel dosing, indications, interactions, adverse effects, and more

You should not use clopidogrel if you have any active bleeding such as a stomach ulcer or bleeding in the brain. Easprin is used for angina, angina pectoris prophylaxis, ankylosing spondylitis, antiphospholipid … Arthritis Pain is used for angina, angina pectoris prophylaxis, ankylosing spondylitis … Bayer Aspirin is used for angina, angina pectoris prophylaxis, ankylosing spondylitis … Vazalore is used for angina, angina pectoris prophylaxis, ankylosing spondylitis, antiphospholipid … Ecotrin is used for angina, angina pectoris prophylaxis, ankylosing spondylitis, antiphospholipid …

You should not use this medicine if you have any active bleeding such as a stomach ulcer or bleeding in the brain. Plavix may also be used for purposes not listed in this medication guide. Store these medicines and all other medicines in a cool, dry place. To view formulary information first create a list of plans. Adding plans allows you to compare formulary status to other drugs in the same class. DailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use.

Before taking dabigatran,

Clopidogrel side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This medicine may cause allergic reactions, including angioedema, which can be life-threatening and require medical attention. Check with your doctor right away if you have large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs. Consider use of another platelet P2Y12 inhibitor in patients identified as CYP2C19 poor metabolizers. MedlinePlus Connect found the following health information for your request.

  • These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
  • Stopping the medicine could increase your risk of a heart attack or stroke.
  • Be careful when using sharp objects, including razors and fingernail clippers.
  • Your doctor will watch you carefully and will probably tell you to avoid physical activity during this time.
  • Stay away from rough sports or other situations where you could be bruised, cut, or injured.
  • If you suddenly stop taking metoprolol you may experience serious heart problems such as severe chest pain, a heart attack, or an irregular heartbeat.

1 Diminished Antiplatelet Activity in Patients with Impaired CYP2C19 Function

Or you can mix the pellets in small amount of apple juice and have your child drink the entire mixture. If pellets stick to the cup, add a small amount of apple juice and give it to your child. Do not store the mixture of dabigatran pellets and soft food or apple juice; use within 30 minutes after mixing. Metoprolol helps to control your condition but will not cure it. Do not stop taking metoprolol without talking to your doctor.

If you need to stop taking dabigatran, your doctor may prescribe another anticoagulant (‘blood thinner’) to help prevent a blood clot from forming and causing you to have a stroke. People with clopidogrel resistance who receive clopidogrel are at risk of serious, sometimes fatal, complications. These individuals may have another heart attack or stroke caused by abnormal blood clot formation; those with stents can develop blood clots (thromboses) within the stents, impeding blood flow. Blood thinners are medicines that prevent blood clots from forming. It’s important to treat blood clots, because clots in your blood vessels and heart can cause heart attacks, strokes, and blockages. High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body.

  • This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
  • The extended-release tablet and extended-release capsule are usually taken once a day.
  • Make sure to refill your prescription before you run out of medication so that you will not miss doses of dabigatran.
  • It works by slowing the production of platelets in the body.
  • These individuals may have another heart attack or stroke caused by abnormal blood clot formation; those with stents can develop blood clots (thromboses) within the stents, impeding blood flow.

This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Blood tests may be needed to check for unwanted effects. MedlinePlus Connect links to health information from the National Institutes of Health and other federal government agencies. MedlinePlus Connect also links to health information from non-government Web sites. See our disclaimers about external links and our quality guidelines.

clopidogrel: medlineplus drug information

Postmarketing Reports

Physical examination revealed normal vitals and no neurological deficits. Laboratory results were unremarkable, with stable hemoglobin levels, normal renal function, and normal clopidogrel: medlineplus drug information coagulation parameters. Hematuria was the only clinical manifestation that resolved spontaneously. Clopidogrel keeps your blood from coagulating (clotting) and can make it easier for you to bleed, even from a minor injury. Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking.

Plavix

Do not take more or less of it or take it more often than prescribed by your doctor. The CYP2C19 gene provides instructions for making an enzyme that is found primarily in liver cells. It is active in a cell structure called the endoplasmic reticulum, which is involved in protein processing and transport. The CYP2C19 enzyme plays a role in the processing of many drugs, including clopidogrel. The CYP2C19 enzyme helps to convert clopidogrel to its active form, which is necessary for the drug to function in the body. In its active form, clopidogrel prevents (inhibits) the function of a receptor protein known as P2RY12 that is found on the surface of platelets.

Enhancing Healthcare Team Outcomes

Your health care provider will choose which one of these medicines are best for your problem. One case report details the course of a 55-year-old male who ingested 4200 mg of clopidogrel (56 tablets of 75 mg) in a suicide attempt. Upon presentation, the patient was asymptomatic, with no signs of major or life-threatening bleeding. He reported pinkish-red urine but no rectal, nasal, or gingival bleeding or hemoptysis.

12inhibitor in patients identified as CYP2C19 poor metabolizers. (

Tell your doctor if you experience any unusual problems while you are taking this medication. These maybe symptoms of a rare and serious condition called thrombotic thrombocytopenic purpura (TTP). If you need surgery or dental work, tell the surgeon or dentist ahead of time that you take Plavix.

Who Should Take Antiplatelet Drugs

It is important to make sure that you’re taking enough medicine to prevent clots, but not so much that it causes bleeding. Your doctor will probably start you on a low dose of carvedilol and gradually increase your dose to allow your body to adjust to the medication. Talk to your doctor about how you feel and about any symptoms you experience during this time.

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